<i>CDKN2B</i> Methylation and Aortic Arch Calcification in Patients with Ischemic Stroke

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CDKN2B Methylation and Aortic Arch Calcification in Patients with Ischemic Stroke

AIM CDKN2A/2B near chromosome 9p21 has been proposed as a potential genetic etiology for both atherosclerosis and arterial calcification. DNA methylation, which can change the expression of CDKN2A/2B, may be an underlying mechanism for this association. This study aimed to evaluate whether CDKN2A/2B methylation is related to aortic arch calcification (AAC) in patients with ischemic stroke. ME...

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Aortic arch calcification, procedural times, and outcomes of endovascular treatment in patients with acute ischemic stroke.

OBJECTIVE To determine the frequency of aortic arch calcification and it's relationship with procedural times, angiographic recanalization, and discharge outcomes in acute ischemic stroke patients undergoing endovascular treatment. METHODS The thoracic component of computed tomographic (CT) angiogram were reviewed by an independent reviewer to determine presence of any calcification; and the ...

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Aortic arch atheroma progression and recurrent vascular events in patients with stroke or transient ischemic attack.

BACKGROUND It is not known whether progression of aortic arch (AA) atheroma is associated with vascular events in patients with stroke or transient ischemic attack (TIA). METHODS AND RESULTS AA atheroma was detected on baseline transesophageal echocardiogram in 167 consecutive patients who had prevalent stroke or TIA. Of these, 125 consented to a follow-up transesophageal echocardiogram at 12...

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Aortic arch atherosclerotic lesions and the recurrence of ischemic stroke.

BACKGROUND AND PURPOSE Aortic arch atherosclerotic lesions are often associated with embolic brain infarction. We investigated the relationship between stroke recurrence and the characteristics of aortic arch atherosclerotic lesions. METHODS Among 487 stroke patients who underwent transesophageal echocardiography, 283 patients with brain embolism diagnosed without significant occlusive lesion...

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Atherosclerotic aortic arch plaques in acute ischemic stroke.

BACKGROUND Atherosclerotic aortic arch plaques (AAP) have been linked to an increased risk of thrombo-embolic events as a cause of acute ischemic stroke of undetermined etiology. OBJECTIVES To find out the presence of atherosclerotic plaques in aortic arch and their potential role as a source of embolism in cerebral infarction of undetermined etiology. METHODS We performed trans-esophageal ...

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ژورنال

عنوان ژورنال: Journal of Atherosclerosis and Thrombosis

سال: 2017

ISSN: 1340-3478,1880-3873

DOI: 10.5551/jat.36897